Research paper database - The Healthy Feet Website

The Healthy Feet programme’s advice centres on EBVM and using the most up to date resources to inform decisions and advice given. We have collated some useful resources on some of the key principles taught.

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Research paper database

Below is a comprehensive library of over 2500 research papers related to foot health in cattle herds. This has been compiled from several systematic reviews* with some extra publications added from a personal collection (NJB).

Use the search box below to find the papers you are interested in. You can also leave comments about individual papers by clicking on their title in the table below.

If you have queries about any of the papers, or would like to suggest papers for inclusion in this list, please contact zoe.herdhealth@gmail.com

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Title	Authors	Full title	All authors	Journal	Year	Description
2 Outbreaks of Fluorosis in Cattle and Sheep	Botha, C. J., Minnaar, P. P., Naude et al	2 Outbreaks of Fluorosis in Cattle and Sheep	Botha, C. J., Minnaar, P. P., Naude, T. W., Vanamstel, S. R., Vanrensburg, S. D. J.	Journal of the South African Veterinary Association-Tydskrif Van Die Suid-Afrikaanse Veterinere Vereniging	1993	Two outbreaks of fluorosis in cattle and sheep were investigated in the Norther Transvaal. The animals exhibited severe dental lesions, lameness and exostoses. Plasma fluoride concentrations were high and there was an inversion of the albumin/globulin ratio. Alkaline phosphatase activity was elevated.Drinking water from boreholes contained excessive amounts of fluoride and upon irrigation, pastures were also contaminated with fluoride
5α-Estrane-3β,17β-diol and 5β-estrane-3α,17β-diol: Definitive screening biomarkers to sign nandrolone abuse in cattle?	Dervilly-Pinel, Gaud, Hewitt et al	5α-Estrane-3β,17β-diol and 5β-estrane-3α,17β-diol: Definitive screening biomarkers to sign nandrolone abuse in cattle?	Dervilly-Pinel, Gaud, Hewitt, S. Armstrong, Kennedy, D. Glenn, Le Bizec, Bruno, Monteau, Fabrice, Rambaud, Lauriane, Sitthisack, Parina	The Journal of Steroid Biochemistry and Molecular Biology	2011
DEVELOPMENT OF HOOF PATHOLOGIES IN DAIRY CATTLE WITH AND WITHOUT ACCESS TO PASTURE	Baird, L. G.	DEVELOPMENT OF HOOF PATHOLOGIES IN DAIRY CATTLE WITH AND WITHOUT ACCESS TO PASTURE	Baird, L. G.	Animal Science	2004
EFFECT OF THE FREQUENCY OF SOLUTION CHANGE IN WALK THROUGH FOOTBATHS	Bathina, H.,, Hemling, T., Janowicz, P.,	EFFECT OF THE FREQUENCY OF SOLUTION CHANGE IN WALK THROUGH FOOTBATHS	Bathina, H.,, Hemling, T., Janowicz, P.,	Ruminant lameness symposium	2006
Efficacy of the Non-antibiotic Paste Protexin Hoof-Care for Topical Treatment of Digital Dermatitis in Dairy Cows	Hofmann-Parisot, M., Kopfler, J et al	Efficacy of the Non-antibiotic Paste Protexin Hoof-Care for Topical Treatment of Digital Dermatitis in Dairy Cows	Hofmann-Parisot, M., Kopfler, J, Pospichal, M.	J. Vet. Med. A	2004
Multidisciplinary approach to dairy herd health and productivity management.	Kelly, J. M., Whitaker, D. A.	Multidisciplinary approach to dairy herd health and productivity management.	Kelly, J. M., Whitaker, D. A.	British Society of Animal Science Occasional Publication	2001
Recent studies on the epidemiology of lameness.	Ward, W.R.	Recent studies on the epidemiology of lameness.	Ward, W.R.	Proceedings of the VIIIth International Symposium on Disorders of the Ruminant Digit and International Conference on Bovine Lameness	1994
[A combination hoof-tester for cattle claws and horse hooves. Contribution to the the diagnosis of lameness in cattle]. [German]	Knezevic, P.	[A combination hoof-tester for cattle claws and horse hooves. Contribution to the the diagnosis of lameness in cattle]. [German]	Knezevic, P.	Wiener Tierarztliche Monatsschrift	1966
[Bovine sole ulcer: a literature review]	Lischer, C. J., Ossent, P.	[Bovine sole ulcer: a literature review]	Lischer, C. J., Ossent, P.	Berl Munch Tierarztl Wochenschr	2001	Sole ulcers are the most frequently encountered lesion in lame cattle. They are of growing concern to the dairy industry since the incidence of ulcers is increasing. Ulcers cause financial losses, the animal's wellbeing is disturbed to a high degree and they harm the image of the industry in general. Biomechanic factors and laminitis are of particular significance in the pathogenesis of the sole ulcer. The development of sole contusions and ulcers is assumed to occur in 3 phases (Sinking theory). In the first phase there is a general disturbance in the vascular system of the corium. The second phase follows when the structures that suspend the claw bone within the horn shoe give way. The locus minoris resistentiae has yet to be identified. The claw bone sinks and causes various lesions when it pinches the underlying sole or heel corium. The third phase begins when haemorrhages become visible on the horn surface of the sole or when the sole ulcerates; socalled third phase lesions. The relationship between the development of sole ulcers and anatomical structures such as the claw bone's tuberculum flexorium or the fat bodies under the bone are unclear. Epidemiological studies have shown that sole ulcers have a high rate of recurrence. The healing processes and the factors that influence them have hitherto not been studied
[Cattle lameness in the USA]. [German]	Amstutz, H. E.	[Cattle lameness in the USA]. [German]	Amstutz, H. E.	DTW - Deutsche Tierarztliche Wochenschrift	1974
[Characterization of the pathology of lactating cows based on the level of lactation. Principal factors in the variation and...	Landais, E.	[Characterization of the pathology of lactating cows based on the level of lactation. Principal factors in the variation and typing of pathologic profiles of lactation]. [French]	Landais, E.	Annales de Recherches Veterinaires	1989	The health disturbances investigated were observed during a long-term trial (six years) conducted at an experimental station located at 1,100 m elevation. The study dealt with 487 lactations involving 190 cows of the Montbeliarde and French Friesian breeds, which produced on average 4,200 kg milk per lactation. The disturbances concerned 59% of monitored lactations, with a mean incidence of 2.1 disturbances per lactation. Lameness and mastitis accounted respectively for 52 and 24% of the clinical affections. Pathology was significantly influenced by breed, basic diet (hay or grass silage), concentrate quantities, lactation rank and year. The authors describe a method permitting an independent analysis of the effects of lactation stage and of season on mastitis and lameness frequency, by limiting the biases due to grouping of calvings and to culling. The study of lactations affected by several pathological disturbances shows that the different types of affections recorded are mutually independent but that successive occurrences of the same affection are not. On the basis of these results, the authors have proposed to globally characterize the "pathological profiles" of lactations
[Claw disorders in a Norwegian dairy herd: A case study.] Klauvproblemer i en norsk storfebesetning: En kasusbeskrivelse	Fjeldaas, Terje, Forshell, Kerstin Plym et al	[Claw disorders in a Norwegian dairy herd: A case study.] Klauvproblemer i en norsk storfebesetning: En kasusbeskrivelse	Fjeldaas, Terje, Forshell, Kerstin Plym, Hjorungdal, Kjell Magne, Kleppa, Anna Lena	Norsk Veterinaertidsskrift	2001	A case study from a Norwegian dairy herd with chronic claw disease problems, for the first time confirmed the diagnosis "digital dermatitis/papillomatous digital dermatitis", including findings of Treponema spp.. The problems had been ongoing since 1995. One animal, which was purchased in 1995, was emergency slaughtered after one year with severe claw problems. Since then the claw problems in the herd aggravated in spite of several attempts to stop them. At a herd investigation in May 2000, 29 claw diseases were diagnosed in 18 cows/heifers. Twelve animals had digital dermatitis, 12 had heel horn erosions, 4 had hemorrhages of the sole and one suffered from corns. Cows with moderate digital dermatitis were treated locally with oxytetracyclin, and cows with heel horn erosions/ slight digital dermatitis were treated with ordinary wood tar/CuSO4, after trimming. Biopsies demonstrated digital dermatitis/papillomatous digital dermatitis with hyperkeratosis and slender spiral organisms, immunoreactive to California PDD-associated Treponema spp. strains (kindly examined at California Animal Health & Food Safety Laboratory System (CAHFS) in San Bernardino, USA.) This is the first time this organism is diagnosed in Norwegian cattle and confirms the suspicion that digital dermatitis may exist in the country. The farmer was recommended to follow up claw trimming and feeding routines and to introduce a body scoring system together with other preventive measures to stop further spreading of the infection. Half a year later, all the animals in the herd were recontrolled. Two cows had slight hemorrhages of the sole, and only one animal had slight symptoms of digital dermatitis
[Clinical and subclinical lameness in young fattenin cattle]	Martens, H., Siering, W., Volker, H.	[Clinical and subclinical lameness in young fattenin cattle]	Martens, H., Siering, W., Volker, H.	Berl Munch Tierarztl Wochenschr	2000	Time dependent changes of subclinical and clinical lameness were analysed in 493 fattening bulls in three different herds with a total number of 30,621 animals. In the majority of cases subclinical lameness were observed which were caused by metabolic acidosis or deficiencies in mineral intake (P and probably Ca). The activity of alkaline phosphatase in plasma exhibited an increase and the dry matter in bone (tubera coxae) a decrease before the appearance of clinical symptoms. Changes in bone composition were accompanied by alterations of plasma Ca and P concentrations, which finally led to clinical lameness. Hence the diagnosis was verified by simple laboratory methods as the precondition for successful treatment and prophylaxis of lameness caused by metabolic disorders
[Clinical findings of cows who originated from dairy herds with chronic wasting disease.]	Muller, K. E.	[Clinical findings of cows who originated from dairy herds with chronic wasting disease.]	Muller, K. E.	Tijdschr Diergeneeskd	2001	Since Spring 1999, a number of dairy farms have reported problems with wasting in cattle. After calving, the physical condition of the cows deteriorated for reasons unknown. Chronic wasting is also associated with disorders such as lameness, abortion, endometritis, mastitis, and respiratory problems. Between April 1999 and March 2000, 19 cows were sent to the Faculty of Veterinary Medicine for further investigation of the chronic wasting. Clinical and pathological investigations resulted in a broad range of diagnoses such as mastitis, abomasal displacement, and claw disorders. The latter, characterised severe laminitis, were predominant and could explain a number of secondary symptoms (inflammation of the bursa, metastatic processes). There were no clear consistent changes compatible with a certain agent, with the exception of one case in which a virus was shown to be the causative agent. The results indicate that wasting disease is not a distinct entity but is characterized by a broad range of diseases in which acute laminitis may be the original problem. The disease profile of chronic wasting disease is very similar to that of 'concrete disease' described by Rebhun in 1995
[Clinical findings of cows who originated from dairy herds with chronic wasting disease.]. [Dutch]	Muller, K. E.	[Clinical findings of cows who originated from dairy herds with chronic wasting disease.]. [Dutch]	Muller, K. E.	Tijdschrift Voor Diergeneeskunde	2001	Since Spring 1999, a number of dairy farms have reported problems with wasting in cattle. After calving, the physical condition of the cows deteriorated for reasons unknown. Chronic wasting is also associated with disorders such as lameness, abortion, endometritis, mastitis, and respiratory problems. Between April 1999 and March 2000, 19 cows were sent to the Faculty of Veterinary Medicine for further investigation of the chronic wasting. Clinical and pathological investigations resulted in a broad range of diagnoses such as mastitis, abomasal displacement, and claw disorders. The latter, characterised severe laminitis, were predominant and could explain a number of secondary symptoms (inflammation of the bursa, metastatic processes). There were no clear consistent changes compatible with a certain agent, with the exception of one case in which a virus was shown to be the causative agent. The results indicate that wasting disease is not a distinct entity but is characterized by a broad range of diseases in which acute laminitis may be the original problem. The disease profile of chronic wasting disease is very similar to that of 'concrete disease' described by Rebhun in 1995
[Clinical picture and differential diagnosis of foot and mouth disease in cattle]	Doll, K.	[Clinical picture and differential diagnosis of foot and mouth disease in cattle]	Doll, K.	Dtsch Tierarztl Wochenschr	2001	Foot-and-mouth disease (FMD) in cattle is characterized by the formation of vesicles and erosions in the mouth, teats and feet. Despite extremely high morbidity, mortality in adults is usually very low, however up to 50% of calves dies due to cardiac involvement or secondary infections. This paper describes the signs of FMD in cattle as well as those of other diseases which causes similar lesions in this species
[Continuing eco-pathological survey: 5. Demonstration of pathologic associations in dairy cow stock: individual data]. [French]	Faye, B.	[Continuing eco-pathological survey: 5. Demonstration of pathologic associations in dairy cow stock: individual data]. [French]	Faye, B.	Annales de Recherches Veterinaires	1986	The calculation of pathological association ratio (or relative risk) from two ways contingency tables, allowed to show numerous interrelationships between diseases of 1,205 dairy cows. The analysis concerns the animal during productive life, the lactation (all lactation mixed), a particular one (1st, 2nd, 3rd and more) and the beginning of productive life of cow (three first lactations). The relationships are discussed according to the level of calculation (animal, lactation, or beginning of life). There is some triangular relations: calving trilogy (dystocia-stillbirth-retained placenta), infectious trilogy (foul of the foot-metritis-mastitis), metabolic trilogy (appetite disorders-ketosis-digestive disorders), foot disorders trilogy (lameness-non infectious diseases of foot-foul of the foot). These pathological groups seem to depend from common risk factors (climate-feeding-cowshed hygiene-control of heat-age-culling policy-genetic factors-anatomical or physiological predisposition, animal size...), but, numerous interactions between groups are also shown, leading to consider pathology in farm like a complex entity
[Continuing eco-pathological survey: 9. Influence of the level of production on the pathology of the dairy cow]. [French]	Barnouin, J.	[Continuing eco-pathological survey: 9. Influence of the level of production on the pathology of the dairy cow]. [French]	Barnouin, J.	Annales de Recherches Veterinaires	1986	Observations are made, during the Eco-Pathological Survey (EEPC), about six main clinical diseases of the dairy cow in the aim of studying the relationships between the milk yield level, the milk fat content, and the susceptibility to the major pathological problems (mastitis, metritis, retained placenta, lameness, digital infections, milk fever). Lactations from Black-Pied cows (1,036) and from Red-Pied ones (Montbeliardes, Tachetees de l'Est) (203) are analysed, and breed and lactation number effects are assessed. As a general trend, disease incidence increases with milk yield. For cows in the 2nd lactation or more, maximum daily milk yield increases with increasing number of diseases occurrences during the lactation: cows free of the six studied diseases produce 28 kg vs 29.2 kg for females with one disease, 30.2 kg when two diseases occurred, 31.9 kg for three diseases or more (P less than or equal to 0.001). Mastitis, lameness and digital infections appear as diseases linked with "high yield" (risk threshold between 30 and 35 kg of maximum daily milk yield). The average milk fat content of the cows free of pathology is 1 to 3% higher compared with affected animals. Relationships between milk yield level and susceptibility to disease seem to be included in the definition of the dairy herd of the future
[Deforming idiopathic ankylosis of the coffin joint in young cattle]. [German]	Nuss, K.	[Deforming idiopathic ankylosis of the coffin joint in young cattle]. [German]	Nuss, K.	Tierarztliche Praxis - Supplement	1994	Case reports are given of a deforming ankylosis of the distal interphalangeal joints in two juvenile cattle of the breed German Simmental. In one animal all distal interphalangeal joints were affected; in the second animal the coffin joints of the forelimbs and the lateral coffin joints of the hindlimbs were ankylosed or in the process of being bridged by bone. The condition was painful, resulting in lameness and loss of weight. Clinical, radiological and pathological-anatomical features are described
[Diaphyseal sequestration of the hollow bones in cattle]. [German]	Hirsbrunner, G.	[Diaphyseal sequestration of the hollow bones in cattle]. [German]	Hirsbrunner, G.	Tierarztliche Praxis - Supplement	1995	Between 1990 and 1993 ten cows with diaphyseal sequestration of the metacarpal or metatarsal bone were brought to the Clinic for Food Animals and Horses, University of Bern. History, clinical and radiographic findings at admission, therapy, and clinical and radiographic short- and longterm results were evaluated retrospectively. Six animals had a history of trauma. The metatarsal bone (n = 9) was much more frequently affected than the metacarpal bone (n = 1). Lameness was slight in seven cases and intermediate in three cases. Soft tissue swelling was present in all cases, and fistula formation in eight cases. Sequestrectomy was performed in nine cases, the exuberant new bone circumferentially removed in three of these cases, and the skin primarily closed in all nine cases treated surgically. One animal with a small sequestrum, showing no fistula formation, was treated conservatively. Four to 44 months after surgery, interviews with the owners by telephone revealed that the recovery had been satisfactory in all ten cases. At the same time period, clinical and radiographic examinations of the six animals that were still alive were performed by a veterinarian additionally. Normal limb function had been restored in all six animals, although the affected limb was clearly distinctable from the unaffected contralateral limb, because of its increased diameter. From the results of this study we concluded that longterm prognosis after sequestrectomy is favourable; primary wound closure can be attempted with good success. Cosmetically promising results, however, can only be achieved, if sequestrectomy is performed early enough in the course of the disease or if the exuberant new bone is surgically removed

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*Hirst (Liverpool University) and Potterton