By Farca, A. M. and Girardi, C. and Piromalli, G. and Re, G. and Rimella, R. and Trenti, F., ,
Description
Adult dairy cows with interdigital dermatitis were divided into 3 experimental groups and treated with 4 g of sulfamonomethoxine, injected into the jugular vein (group A), or the digital vein (group B), or into the digital vein during and followed by 20 min haemostasis (group C) respectively. Blood samples were collected at scheduled times ( from 1 min to 72 h) and the serum levels of sulfamonomethoxine were measured using a HPLC. The analysis of sulfamonomethoxine time course showed marked differences among the 3 groups. The i.v. injection in the presence of haemostasis induced a local distribution of sulfamonomethoxine in the foot tissues which it was concluded was responsible for the clinical efficacy of this therapeutic method
Adult dairy cows with interdigital dermatitis were divided into 3 experimental groups and treated with 4 g of sulfamonomethoxine, injected into the jugular vein (group A), or the digital vein (group B), or into the digital vein during and followed by 20 min haemostasis (group C) respectively. Blood samples were collected at scheduled times ( from 1 min to 72 h) and the serum levels of sulfamonomethoxine were measured using a HPLC. The analysis of sulfamonomethoxine time course showed marked differences among the 3 groups. The i.v. injection in the presence of haemostasis induced a local distribution of sulfamonomethoxine in the foot tissues which it was concluded was responsible for the clinical efficacy of this therapeutic method
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