By Arfi, L. and Henke, C. L. and Howie, N. M. and Kausche, F. M. and Smith, F. J. and Trenti, F., , 1994
Description
Based on in vitro results ranging from 0.016 to 0.062 `g/ml for the sensitivity of bacteria associated with interdigital necrobacillosis, studies were conducted to test the efficacy in vivo in acute natural infections. Studies presented were conducted in cattle in a number of countries. Cattle were treated with a dose of 1 mg ceftiofur free acid equivalents/kg of body weight at 24-h intervals for 3 consecutive days. No additional treatment was given. Efficacy of the treatment for the individual animal was based of the evaluation of lameness and lesions after the end of the treatment. Estimation of the efficacy of the ceftiofur treatment in the treatment group was based on the comparisons with a pre-established clinical hurdle (i.e. cure rate) which had to be met. Results indicated that ceftiofur sodium is efficacious in the treatment of bovine interdigital necrobacillosis
Based on in vitro results ranging from 0.016 to 0.062 `g/ml for the sensitivity of bacteria associated with interdigital necrobacillosis, studies were conducted to test the efficacy in vivo in acute natural infections. Studies presented were conducted in cattle in a number of countries. Cattle were treated with a dose of 1 mg ceftiofur free acid equivalents/kg of body weight at 24-h intervals for 3 consecutive days. No additional treatment was given. Efficacy of the treatment for the individual animal was based of the evaluation of lameness and lesions after the end of the treatment. Estimation of the efficacy of the ceftiofur treatment in the treatment group was based on the comparisons with a pre-established clinical hurdle (i.e. cure rate) which had to be met. Results indicated that ceftiofur sodium is efficacious in the treatment of bovine interdigital necrobacillosis
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