By Castro, A. E. and Read, D. H. and Sundberg, J. P. and Thurmond, M. C. and Walker, R. L., Veterinary Record, 1992
Description
Preliminary findings from a study of Californian interdigital papillomatosis included the diffuse invasion of superficial stratum spinosum and papillary dermis and some focal invasion of deep papillary and reticular dermis and arterioles by a large number of spirochaetes which resembled treponemes. No papillomaviruses or their antigens were detected and the papillomas responded rapidly to procaine penicillin or ceftiofur with mature papillomas decreasing in size, early papillomas healing and the painfulness of all papillomas vanishing. The possibility that the spirochaetes may play a pathogenic role and the relevance of these findings to 'digital dermatitis' in the UK, Netherlands and Italy and 'interdigital papillomatosis' in North America which have similar features is discussed
Preliminary findings from a study of Californian interdigital papillomatosis included the diffuse invasion of superficial stratum spinosum and papillary dermis and some focal invasion of deep papillary and reticular dermis and arterioles by a large number of spirochaetes which resembled treponemes. No papillomaviruses or their antigens were detected and the papillomas responded rapidly to procaine penicillin or ceftiofur with mature papillomas decreasing in size, early papillomas healing and the painfulness of all papillomas vanishing. The possibility that the spirochaetes may play a pathogenic role and the relevance of these findings to 'digital dermatitis' in the UK, Netherlands and Italy and 'interdigital papillomatosis' in North America which have similar features is discussed
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